Descripción
The German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) ( https://www.dife.de/en ) is a member of the Leibniz Association. The institute’s mission is to conduct experimental and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for treatment and prevention.The Department of Experimental Diabetology (DIAB) ( https://www.dife.de/en/research/departments-and-labs/experimental-diabetology /) and the Junior Research Group Epigenetics of Obesity and Diabetes (EOD) ( https://www.dife.de/en/research/departments-and-labs/epigenetics-of-obesity-and-diabetes /) invite applications for1 Postdoc (m/f/d)starting January 1, 2027.We are looking for a highly motivated Computational Biologist/Bioinformatician to join our teams, which focus on understanding how obesity and type 2 diabetes reshape the epigenome, with the goal of identifying disease-associated genes and epigenetic alterations. Using lean and obese mouse models and translational validation in humans, we investigate how interventions such as intermittent fasting, endurance training, and bariatric surgery can modulate disease-induced molecular changes.Tasks- Perform end-to-end data analysis, including quality control, data integration and inference of regulatory networks- Analyze and interpret multiome datasets (e. g. transcriptomics, epigenomics and related modalities)- Apply advanced computational and statistical methods for integrative analysis of multi-layer biological data- Develop clear data visualizations, reports and written summaries to communicate results- Collaborate closely with laboratory scientists to translate biological questions into computational analysesSkills and requirements- Excellent master and doctoral degree in Computational Science/Bioinformatics- Strong background in biological fundamentals, including genetics and epigenetics- Experience with multiome data analysis (e